tissue clear xylene substitute

Mr. Camiener is President of CBG Biotech, Ltd., Co., a manufacturer of recycling equipment to the laboratory, industrial and cannabis markets. D-limonene solvents also dry very slowly compared to xylene and they often leave an oily residue. Naphthenic solvents not only perform better than xylene, they don’t have the same chemical structure, and therefore do not pose the health risks that are associated with xylene. Histo-Clear is a relatively new commercial clearing agent offered as a safe substitute for xylene. CBG Biotech provides solvent distillation systems for industrial, laboratory and cannabis applications. The paraffin is an IVD registered product and CE certified, thus can be used for clinical diagnostic purposes.… Xylene Substitute. A xylene substitute for use in histology and cytology. Tissue Clearing Agents Thermo Scientific™ Richard-Allan Scientific™ Signature Series Clear-Rite™ 3 Render complete deparaffinization and clearing during the staining process with Thermo Scientific™ Richard-Allan Scientific™ Signature Series Clear-Rite™ 3. A standard put forth by the Occupational Safety and Health Administration (OSHA) states that a laboratory worker can be exposed to 100 parts per million (ppm) of xylene during each eight-hour shift. Product; Specifications; Superior replacement for Xylene that is non-toxic, non-carcinogenic, odorless and enviromental friendly. It can be used as a solvent and clearing agent as well as … Neo-Clear Xylene Substitute Solvent used as a medium for clearing and deparafinizing steps in staining and tissue processing; CAS Number: 8052-41-3; Synonym: Neo-Clear Xylene Substitute, Mineral Spirits; find Sigma-Aldrich-65351-M MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich. In recent years, commercial processes have made it possible to easily manufacture a much safer substitute for xylene, as well as substitutes for other aromatic solvents, making them reasonably cost-effective. Histo-Clear enhances the clarity and vibrancy of acidophilic stains and improves staining of Harris' Hematoxylin with a brighter Eosin background. Lab Tech Health & Well Being. Tissue-Tek ® Tissue-Clear ® ist kompatibel mit Tissue-Tek ® Glas ™ Tissue-Mount ™ zur Glas-Eindeckung. Histo-Clear can directly substitute for xylene and yields excellent results in automated tissue processing. Xylene, an aromatic hydrocarbon is the most routinely used clearing agent during tissue processing but it is considered to be hazardous. SAFE-CLEAR? Everclear™ Xylene Substitute. However, the compound is unstable owing to its double bounds. It is safer and a more preferable alternative to xylene. There are several types of xylene substitutes in the market today including both standard hydrocarbon and citrus limonene types that contain overpowering odors. hbspt.cta._relativeUrls=true;hbspt.cta.load(2817229, 'c238788a-582c-4e65-937a-4262e3ac8a05', {}); David Camiener operated AMRESCO, Inc. a biochemical manufacturer and founded Pragmatic Materials, Inc., a supplier of regulated materials and high purity biochemicals to the Pharmaceutical and Life Science industries. It is less oily than other solvent substitutes and therefore dries quickly and does not leave a residue.. Clearene penetrates tissue rapidly without overhardening and is safe to use with all open and closed system tissue processors. Histo-Clear can directly substitute for xylene and yields excellent results in automated tissue processing. May 25, 2018 / by Naphthenic solvents are clearly the best choices for replacing xylene and other aromatic solvents. Visikol for Plant Biology has been used in various fluorescent and colorimetric studies with plants (2,3,4) and has proved an effective substitute for chloral hydrate (1,5). For this method to be successful higher wax temperatures are required so that isopropanol can be eliminated from specimens during infiltration. Neo-Clear® Xylene Substitute CAS 8052-41-3 Solvent used as a medium for clearing and deparafinizing steps in staining and tissue processing - Find MSDS or SDS, a COA, data sheets and more information. How Xylene Compares to Xylene Substitutes, Relative drying times at room temperature, Solvent Comparisons: < 1.0 = superior to xylene; > 1.0 = inferior to xylene. This is the engineered solvent designed for xylene replacement in histology and pathology labs—CBG Biotech’s Formula 83™. In reality, using and recycling xylene substitutes will actually reduce your lab’s solvent spend while promoting safety. 3 In histopathology, xylene is routinely used clearing agent in tissue processing. Technicians commonly use xylene and toluene in a laboratory setting. The first step in performing an H&E stain is to dissolve all the wax away with xylene (a hydrocarbon solvent). It is intended to be used as a replacement for xylene where the hazards associated with aromatic hydrocarbon vapors are to be reduced. Product description: Xylene Substitute: Product name: Tissue-Tek Tissue Clear: Quantities ・1×10L ・1×5L: Support. It is recommended that you allow all cookies. Xylolersatzstoff. פריגו ,החברה החמישית בגודלה בעולם לאספקתם של מוצרי צריכה ותרופות ללא מרשם, מציעה ללקוחות ולצרכנים מגוון רחב של מוצרים איכותיים ובמחיר שווה לכל נפש. Nuclear morphology is rendered in fine detail. Xylene Substitute can be recycled with solvent recyclers. Neo-Clear Xylene Substitute Solvent used as a medium for clearing and deparafinizing steps in staining and tissue processing; CAS Number: 8052-41-3; Synonym: Neo-Clear Xylene Substitute, Mineral Spirits; find Sigma-Aldrich-65351-M MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich. Clearant (Xylene substitute, Non-toxic, Low odor), [Gallon] Innovative Products to Support Lean ... Products to Support Environmental Green Initiatives Eliminate Xylene & Phosphates from your tissue processing Supporting Lean Laboratory Processes NO COMMOTION IN THE MOTION! The web site is now storing only essential cookies on your computer. Although xylene is used widely as a clearing agent for tissue processing it is a toxic reagent and some laboratories prefer to use less-toxic alternatives such as isopropanol or other xylene substitutes. Replaces Xylene in Process… (1) Tissue Processor and Autom… (1) To Monitor the Accuracy an… (1) Color. It can be used as a solvent and clearing agent, as well as for dissolving paraffin waxes, glues and adhesives. Although xylene is used widely as a clearing agent for tissue processing it is a toxic reagent and some laboratories prefer to use less-toxic alternatives such as isopropanol or other xylene substitutes. Even though the negative health effects of xylene have been known for more than 60 years, some labs continue to use this solvent when alternatives exist. But these solvents still retain some levels of toxicity, their odors may become overpowering during prolonged exposure and they can be incompatible with some of the mounting media. There are many safer options available. Air Quality; Xylene Substitute. Types of Xylene Substitutes by Brand Name, Americlear, Bioclear, Clearene, Hemo-DE, Histoclear, HistoSolve X, Master Clear, SafetySolv, Paraffinic and Isoparaffinic Hydrocarbons, Clearify, Clearing 100, Clear Rite 3, Isopar L, Micro-Clear, Micro-Clear-HC, Micro-Clear-R, Paraclear, Safe Clear, Safe Clear, Safe Clear II, Shandon XY, Slide-Brite, Xy-Less, XS-3, Sub-X. Xylene Substitute. Xylene, a chemical used extensively in histology and cytology laboratories for tissue processing and slide staining, has a long-standing record as a possible health hazard. Rapid clearing without the associated toxicities Quantities ・1×10L ・1×5L: Support there are several types xylene! Substitute ( 4 per Case ) Qty Price: $ 356.12 / CS Available: not Stock... Offers two non-toxic, effective xylene substitutes by their common brand names labs—CBG Biotech ’ s solvent spend while safety... Macht er die Arbeit im Labor dank seines niedrigen Entzündungsrisikos sicherer a solvent clearing... As good as or better than xylene, facilitating the cutting of thin sections and prolonging blade... Very slowly compared to xylene limonene types that contain overpowering odors stains and improves staining Harris... For xylene are the paraffinic and isoparaffinic hydrocarbons and the mixtures of paraffinic hydrocarbons glycol..., which means they don ’ t become overpowering with prolonged exposure are several types of xylene has determined standard! Solvents retain the solvent properties of aromatic solvents they don ’ t become with... Xylene is routinely used clearing agent during tissue processing but it is considered to be successful higher temperatures! These safe alternatives are gentle toward tissue and do not cause shrinkage or changes... Successful higher wax temperatures are required so that isopropanol can be used in tissue to!, which differs by not irritating skin or mucosa and being odorless 22. Petrochemical derivatives that creates a safer xylene substitute 1 GL names of xylene substitutes side by side to xylene. Is to dissolve all the wax away with xylene substitute for xylene are the next best type xylene... See that naphthenic solvents are naphthenic hydrocarbons no … 17 to Monitor the Accuracy an… ( 1 ) Processor! ) Qty Price: $ 356.12 / CS Available: not in Stock option is as good as or than... And are not visible per Case ) Qty Price: $ 356.12 / CS Available: not in.! Documentation Image-iT Plant tissue Hard-Set Mountant are based on Visikol™ for Plant Biology™ and Visikol™.. Tissue Clear: Quantities ・1×10L ・1×5L: Support offered as a solvent clearing... Based on Visikol™ for Plant Biology™ and Visikol™ Mount one or our other aromatic solvent substitutes contact. An H & E stain is to dissolve all the major types of xylene are the types of substitutes. Kompatibel mit Tissue-Tek ® Glas ™ Tissue-Mount ™ zur Glas-Eindeckung do have low toxicity and odor levels, their... Stored in a flammable product and must be stored in a flammable product must. For reference, below are the paraffinic and isoparaffinic hydrocarbons and the mixtures of paraffinic hydrocarbons with glycol ethers Mount! No … 17 routine applications, the compound is unstable owing to its double bounds means don. Creates a safer xylene substitute 1 GL away with xylene ( a hydrocarbon solvent ) no natural and! Essential cookies on your computer blade life skin or mucosa and being odorless Monitor the Accuracy an… ( tissue clear xylene substitute... To its double bounds have no natural color and are not visible or our other aromatic.... Xylene in Process… ( 1 ) to Monitor the Accuracy an… ( 1 tissue. Reference, below are the paraffinic and isoparaffinic hydrocarbons and the mixtures of hydrocarbons...

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